Why Don’t Edibles Work for Me?

Edibles do not work the same way for every individual. That’s why some people may feel minimal or no effect at all after consuming edibles.

There could be many reasons for this, ranging from the quality of the edibles to your own body’s metabolism.

In this guide, we will briefly try to explain why edibles do not work for some and what alternatives are available as solutions.

What are Edibles

Edibles constitute a diverse array of cannabis-infused products, ranging from enticing gummies and luscious chocolates to savory baked goods.

Unlike the swift effects of smoking or vaping, the consumption of edibles initiates a unique journey through the body involving digestion and metabolism.

How Edibles Work on Your Body

THC and CBD are cannabinoids produced by the cannabis plant that interact with the body’s endocannabinoid system. Inhaled cannabis has a quick activation process in the lungs, whereas edibles, following decarboxylation, are processed by the liver.

THC is converted into 11-hydroxy-THC, a powerful cannabinoid that leads to the delayed onset and perhaps higher effects of edibles.

Factors That May Affect Sensitivity to Edibles

Several factors can influence an individual’s sensitivity to edibles:

1.   Dosage

The concentration of THC or CBD in the edible is critical. Low doses or a strong tolerance might result in diminished effects. Homemade edibles may not have the anticipated potency if calculated incorrectly.

Example: A low THC concentration or incorrectly measured cannabis content in a homemade brownie may result in minimal psychoactive effects.

2.   Metabolism

Variations in metabolism, influenced by factors like genetics, can affect how quickly the body processes cannabinoids. Slow metabolizers may experience prolonged and intense effects.

Example: Genetic testing might reveal whether an individual is a slow metabolizer, explaining why they feel the effects more intensely and for a more extended period.

3.   Tolerance

Regular cannabis users can develop tolerance, requiring higher doses for the same effects. Tolerance breaks or alternative consumption methods can help manage this.

Example: Frequent users might not experience the desired effects from edibles due to an elevated tolerance level.

4.   Incorrect Decarboxylation

Insufficient activation of THC arises from failing to decarboxylate cannabis before producing edibles, resulting in lower potency.

Example: Homemade edibles without proper decarboxylation might lack the necessary THC activation, resulting in a weaker or nonexistent high.

5.   Storage Conditions

Improper storage, exposing edibles or cannabis to heat and light, can degrade cannabinoids over time.

Example: Old or improperly stored edibles may contain lower THC levels, diminishing their potency.

6.   Interaction with Alcohol or Cannabis

Consuming edibles while already intoxicated can mask the effects or lead to an unpleasant experience.

Example: Being crossfaded, a state where alcohol and cannabis effects amplify each other, might overshadow the subtler effects of edibles.

7.   Liver Enzyme Variations

In rare cases, genetic variations in liver enzymes can impact how the body metabolizes cannabis, potentially rendering individuals immune to edibles.

Example: Individuals with specific liver enzyme variations may consistently experience minimal or no effects from edibles due to a unique metabolic process.

Alternatives to Edibles

For those seeking alternatives or faced with unresponsiveness to edibles, various consumption methods offer diverse experiences:

  • Smoking and Vaping: Though they represent significant hazards to the lungs, quick-acting treatments with the capacity to adjust doses are available.
  • Tinctures: Tinctures, which are administered under the tongue, provide a medium ground between foods and inhalation approaches, with a speedier onset.

Safety Precautions when Consuming Edibles

  • Start Low, Go Slow: Begin with low doses and gradually increase to avoid unexpected and overwhelming effects.
  • Mind Your Tolerance: Be aware of your tolerance level and consider tolerance breaks to enhance the effects of edibles.
  • Buy from Licensed Dispensaries: Ensure accurate labeling and quality by purchasing edibles from reputable, legal dispensaries.
  • Proper Storage: Store edibles in a cool, dark place to preserve potency and prevent cannabinoid degradation.


  1. How do you make edibles kick in?

Several factors can impact the onset time of edibles. Consuming edibles on an empty stomach may result in a speedier onset, but it’s important to remember that having a small, balanced meal with some good fats might improve cannabinoid absorption. Furthermore, staying hydrated might improve the overall efficacy of edibles.

  1. Do edibles make eyes red?

Yes, edibles, like smoking cannabis, can induce red or bloodshot eyes. THC is to blame since it can temporarily reduce blood pressure, causing blood vessels to widen. The dilatation of the blood vessels in the eyes causes the typical red-eye effect.

  1. What makes edibles feel stronger?

Several factors can alter the perceived potency of food. The dosage is critical; greater dosages frequently result in more noticeable effects. Individual tolerance, metabolism, and the presence of additional cannabinoids in the edible product might further influence the overall intensity of the experience.

  1. What foods should you avoid when high?

While munchies are a common side effect of cannabis consumption, it’s advisable to avoid overly sugary or greasy snacks, as they might lead to discomfort. Spicy foods can also intensify the psychoactive effects for some individuals.

Opting for balanced, nutritious snacks can enhance the overall well-being during a cannabis experience. Staying hydrated is essential to counteract potential dry mouth, a common side effect of cannabis.


As you can see, there could be many reasons why edibles don’t really make you high. In that case, you can try other methods of ingesting cannabis. If you prefer edibles over other ways to consume weed, then make sure they are stored correctly and have the right dosage.

Photo of author

Nazmul Nahid

Leave a Comment